Corn syrup has been widely used to replace white refined sugar, in an attempt to bypass the harmful effects associated with the calories in sugar, while maintaining the desired sweetness. However, current studies show that high fructose corn syrup may actually contribute more to weight gain, obesity, and other associated disorders, than the conventional sweetener made from cane and beets. To understand the factors that go into such a debate, however, it may be worthwhile to understand the origins of corn syrup and sugar, and the predominant effects of each.